The Specificity of Complement Fixation.

The Mechanism of Complement Fixation

1. Complement fixation is obtained in every antigen-antibody reaction involving the presence or formation of a heterogeneous phase (red cells, bacteria, precipitate). 2. The physical constants of fixation (temperature coefficient, velocity, quantitative relationships between the reactants) are those commonly associated with adsorption processes, and are the same in the three types of fixation s...

Specificity and Sensitivity of the Reiter Protein Complement - Fixation ( Rpcf ) Test *

The reliability of the sero-diagnosis of syphilis depends on the specificity and the sensitivity of the tests used. The specificity of a test is determined by the nature of the antigen; the sensitivity depends mainly on the technique by which the test is performed. The most specific though not the most sensitive test at the moment is, without doubt, the T. pallidum immobilization (TPI) test of ...

The Gomez Complement-fixation Reaction

Much has been done, but there is still much to be accomplished in the matter of tests for infection and immunity in leprosy. To be of help to the clinicians it is not sufficient for a test to be positive among the inmates of a leper asylum; it is necessary that it should work also in free surroundings where are met the doubtful cases, toward the' detection of which the greatest vigilance should...

Indirect Complement Fixation in Foot-and-Mouth Disease

Specificity and sensitivity of the Reiter protein complement-fixation (RPCF) test. Report on 1,400 selected sera.

The reliability of the sero-diagnosis of syphilis depends on the specificity and the sensitivity of the tests used. The specificity of a test is determined by the nature of the antigen; the sensitivity depends mainly on the technique by which the test is performed. The most specific though not the most sensitive test at the moment is, without doubt, the T. pallidum immobilization (TPI) test of ...